Probiotics Show Benefits in Periodontitis Management, reveals meta-analysis
Researchers have found in an umbrella meta-analysis that probiotics supplementation may positively influence periodontal health by improving Bleeding on Probing (BOP) and Clinical Attachment Level (CAL) in individuals undergoing treatment for periodontitis.
Probiotics supplementation has many beneficial impacts on periodontitis outcomes. This umbrella meta-analysis evaluated the effectiveness of probiotics in treating periodontitis, focusing on primary outcome measures, including reductions in probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), plaque index (PI), gingival index (GI), and PDD reduction in medium and deep pockets.
All meta-analyses evaluating the impact of probiotics supplementation on periodontitis outcomes were considered eligible. A random-effects model was employed to estimate the pooled results. Subgroup and sensitivity analyses were conducted.
The quality of the studies was evaluated using the AMSTAR2 tool. Overall, 19 meta-analyses with 67 data sets were included in this umbrella review. Our findings indicated that probiotics supplementation significantly decreased BOP (effect size [ES]: −8.20; 95% CI: −15.10 to −1.31; P = .02) and CAL after sensitivity analysis (ES: −0.52; 95% CI: −0.75 to −0.28; P < .05). No other significant effect was observed on PPD, PI, GI, or PDD reduction in medium and deep pockets.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.