Vitamin D deficiency linked with early-onset periodontitis: A case report

Written By :  Dr. Shravani Dali
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2023-10-10 14:30 GMT   |   Update On 2023-10-11 07:30 GMT
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The early-onset periodontitis may be associated with micronutrient abnormalities including Vitamin D deficiency suggests a case reported by researchers  and the same has been published in the Medicine.

Periodontitis is an inflammatory disease with multifactorial etiology. Vitamin D, a fat-soluble vitamin, has protective effects on inflammatory response in various systemic conditions. The clinical features of vitamin D deficiency include growth failure, hypotonia, pathologic fractures, rachitic rosary, tetany and so on. Here we present a case of 12-year-old girl affected by early-onset periodontitis accompanied with vitamin D deficiency.

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According to  the history, a 12-year-old girl reported  with gingival redness, bleeding associated with tooth brushing, and mandibular anterior teeth movement, with difficulty in mastication for the past 2 months to the attending doctors. There is no relevant family history or special systemic disease history. The serological microelement test showed vitamin D levels were significantly lower than normal range. Also  Immunological test showed abnormal CD4+/CD8+(CD3+CD4+/CD3+CD8+) ratio as well.

Based on the clinical and serological findings, this patient was ultimately diagnosed with early-onset periodontitis accompanied with vitamin D deficiency.

The main treatments for this patient were 3-fold: periodontal therapy, vitamin D supplement and oral hygiene instructions. Following 1-year therapy, periodontal conditions recovered and became stable. And serological vitamin D levels returned to normal range.

The case of interest serves as an important reminder to clinicians, that the early-onset periodontitis may be associated with micronutrients abnormalities, and early-diagnosis and treatment could avoid the body heathy disorders.

Reference:

Li, Chen PhDa; Zhang, Jinmei PhDa; Wang, Lufei PhDb; Yang, Jingmei PhDa,*. A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review. Medicine 102(39):p e35321, September 29, 2023. | DOI: 10.1097/MD.0000000000035321

Keywords:

Li, Chen PhDa; Zhang, Jinmei PhDa; Wang, Lufei PhDb; Yang, Jingmei, case, early-onset, periodontitis, vitamin D deficiency, case report, literature review, Medicine

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