Rare case of childhood bullous pemphigoid mimicking toxic epidermal necrolysis: a report
Iran: A recent case study in the journal Case Reports in Dermatological Medicine describes the case of a childhood bullous pemphigoid (BP) that clinically mimicked toxic epidermal necrolysis (TEN). The case shows that juvenile BP should be considered in the differential diagnosis of TEN in children, particularly if there are unusual features and an intractable course.
Bullous pemphigoid is an acquired autoimmune bullous disorder observed rarely in pediatric population. It is usually presented as large and tense bullae, distributed predominantly in the acral areas.
In the study, Zahra Nikyar, Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran, and colleagues present the case of a 3-year-old patient with an atypical presentation of BP whose clinical features were perplexing and provided a distinct diagnostic challenge.
The patient was referred to Markaz e Tebi Atfal, Tehran University of Medical Sciences (TUMS), Tehran, Iran, at February 2021, when she was ill with generalized erythematous patches, plaques, and flaccid bullae filled with clear fluid, along with some erosions, distributed all over her body. Nikolsky's sign was positive.
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