Add on Estradiol to 2% minoxidil offers no additional advantage in Female pattern hair loss, suggests study
A new study published in the Clinical and Experimental Dermatology journal showed that estradiol with minoxidil (EMX) may raise the risk of irregular menstruation in individuals with female pattern hair loss (FPHL) which is also known as female androgenetic alopecia (AGA). The variables that influence miniature follicle development and the pathophysiology of FPHL are yet unknown. There is proof that genetic, hormonal, and environmental factors also play a part in male AGA, in addition to the most obvious impact of androgens. Women who have thick, healthy hair are more likely to feel secure, confident, and capable of change. They are also more likely to engage with others.
The prevalence of female pattern hair loss is high and has a detrimental effect on one's quality of life. The most effective treatment for FPHL is minoxidil, however it is more difficult to treat than male pattern hair loss. Several trials treated FPHL with 17α-estradiol solution, either by alone or in combination with minoxidil, with varying degrees of success. Thus, this study evaluated the safety and effectiveness of topical 17α-estradiol 0.01% with minoxidil 2% against minoxidil 2% in the treatment of FPHL, by Nermeen Ibrahim Bedair and colleagues.
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