Air pollutants linked to increased risk of Atopic dermatitis: AAD study
Long-term exposure to air pollutants, including gases and particulate matter, is an independent risk factor for developing Atopic dermatitis (AD), according to a new study.
The findings have been elaborated in the Journal of American Academy of Dermatology
Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease and a growing health concern, because of its high prevalence and associated low quality of life. Genetic predisposition, environmental triggers, or interactions between them contribute to the pathophysiology of Atopic dermatitis (AD).
Both indoor and outdoor air pollution, which are of increasing concern with urbanization, are well-known environmental risk factors for asthma, whereas there is relatively little evidence in AD. It is very important to identify and control risk factors from the environment in susceptible subjects for successful treatment and prevention.
Accumulating evidence now suggests that a variety of air pollutants, such as environmental tobacco smoke, volatile organic compounds, formaldehyde, toluene, nitrogen dioxide, and particulate matter, act as risk factors for the development or aggravation of AD. These air pollutants probably induce oxidative stress in the skin, leading to skin barrier dysfunction or immune dysregulation. However, these results are still controversial because of the low number of studies. To date, little evidence is available to strongly determine whether atopic dermatitis (AD) can be caused by exposure to air pollutants, including gases and particulate matter.
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