Alcohol misuse tied to poor treatment response in patients with psoriasis: Study
Alcohol misuse is associated with poor treatment response in patients with psoriasis, suggests a study published in the British Journal of Dermatology.
Factors that might influence response to systemic treatment for moderate-to-severe psoriasis are varied, and generally, are poorly understood, aside from high body weight, suggesting that other unidentified factors may be relevant in determining response to treatment. The impact of alcohol misuse on treatment response has not been previously investigated.
A group of researchers from the U.K conducted a study to investigate whether alcohol misuse is associated with poor response to treatment for psoriasis.
This was a prospective cohort study in which response to systemic therapies was assessed using the Psoriasis Area and Severity Index (PASI). The CAGE (Cut down, Annoyed, Guilty, Eye-opener) questionnaire was used to screen for alcohol misuse. A multivariable factional polynomial linear regression model was used to examine factors associated with a change in PASI between baseline and follow-up.
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