Apremilast safe for psoriasis in elderly patients: study claims
According to a retrospective, real-world study, Apremilast, a drug recently developed for psoriasis have proved to be effective and safe in elderly patients with psoriasis.
Researchers have published the findings of research in Drugs And Aging.
Psoriasis is a chronic inflammatory dermatosis with a waxing and waning course. The management of psoriasis has witnessed a tremendous change over the last decade paving ways to the newer biological agents. The immunosuppressive effects on chronic usage of certain corticosteroids like methotrexate, acitretin, and cyclosporine have led researchers to explore new, less toxic drugs for the elderly with psoriasis.
Although Apremilast (Otezla; Celgene) was approved by the US Food and Drug Administration (FDA) on March 21, 2014, for the management of active psoriatic arthritis (PsA) in adults, there is a paucity of information on this drug, especially in the Indian literature.
Céline Phan et al carried out the study to comprehensively yet concisely evaluate the various clinical aspects of apremilast use in psoriasis and inflammatory skin diseases, particularly for the geriatric patients.
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