Benzoyl Peroxide and Retinol Regimen is Effective for Acne Vulgaris
Benzoyl peroxide is an FDA approved skincare ingredient that's widely used for the topical treatment of acne. In a recent study presented at the American Academy of Dermatology (AAD) Virtual Meeting Experience, the researchers have reported that the combination of 2.5 benzoyl peroxide and a stabilized cosmetic retinol significantly improves lesion count reduction after 12 weeks.
The first-line topical treatment for mild to moderate acne that dermatologists recommend is a combination of benzoyl peroxide (BPO) to target the bacteria, and a retinoid, to promote surface cell turnover. Researchers of Johnson & Johnson conducted a study to evaluate the efficacy and tolerance of a daily regimen of 2.5% BPO and a stabilized cosmetic retinol for its ability to improve acne and overall complexion in patients (aged 12-30) with mild to moderate acne.
It was a 12-week, multi-centre, evaluator-blinded clinical study with 33 participants with mild to moderate acne vulgaris on the face. All patients had between 10-100 non-inflammatory plus 10-50 inflammatory lesions. The researchers used Investigator Global Acne (IGA) assessment in addition to other efficacy assessments and self-assessments. The major outcome assessed was a per cent change from baseline to week 12 in total lesion counts. During the course of the study period, patients applied benzoyl peroxide in the morning and cosmetic retinol in the evening (each only once daily) for 12 weeks.
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