Bleomycin and lidocaine delivered via needle-free EPI viable treatment of recalcitrant keloids
Keloids are scars that extend beyond the confines of the original wound or trauma caused by chronic dermal inflammation. They can lead to physical and psychosocial distress, affecting a patient's quality of life through symptoms like pain, itching, functional impairment, and appearance.
According to a recent study published in Lasers in Surgery and Medicine, EPI-assisted (electronically-controlled pneumatic jet-injector) treatment with bleomycin and lidocaine is an effective, well-tolerated alternative to conventional needle injectors (CNI) in recalcitrant keloid scars cases. Based on the study findings, this option is viable and well-operated in such cases.
The treatment of keloids can be challenging. Intralesional bleomycin using CNI is effective but is associated with disadvantages. It requires repetitive and painful injections. This study evaluated the effectiveness, tolerability, and patient satisfaction of intralesional bleomycin with lidocaine administered using EPI in recalcitrant keloids.
This retrospective study involved patients who received three intralesional EPI-assisted treatments with bleomycin and lidocaine. Patient and Observer Scar Assessment Scale (POSAS) at baseline and four to six weeks after the third treatment evaluated the effectiveness. Pain scores, adverse effects, patient satisfaction, and the Global Aesthetic Improvement Scale (GAIS) were also assessed.
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