Botulinum Toxin Type A Shows Promise as Add-On Treatment for HS, reports research
Botulinum toxin type A may help reduce inflammation in hidradenitis suppurativa (HS) by inhibiting mast cell degranulation. Recent findings suggest its potential as an off-label add-on treatment, showing positive outcomes for patients suffering from hidradenitis suppurativa.
A recent study found that the off-label use of botulinum toxin type A (BoNT-A) can be an effective add-on treatment for symptom control in patients with hidradenitis suppurativa (HS). Led by Noor F. Goandal from Zealand University Hospital, the study highlights the continued need for alternative therapies despite the availability of biologics like secukinumab, adalimumab, and bimekizumab. BoNT-A, known for treating hyperhidrosis, may also reduce inflammation by inhibiting mast cell degranulation, a key factor in HS severity.
The retrospective case series analyzed eight HS patients treated with BoNT-A between 2018 and 2023. Investigators assessed treatment efficacy using numeric rating scales (NRS) and a Likert scale to evaluate suppuration, pain relief, and effects on daily activities. Participants reported high satisfaction with a median NRS score of 8.5. A moderate reduction was noted among six patients with suppuration (median NRS 6.5).
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.