Concentrated growth factor effective in patients with androgenic alopecia
Concentrated growth factor (CGF) is a newer second generation platelet concentrate that is prepared by centrifuging blood samples at alternating and controlled speeds using a special centrifuge. Differential centrifugation results in the formation of a denser fibrin matrix richer in growth factors than those observed in the PRF and PRP.
Concentrated growth factor treatment is effective, safe, and worth popularizing in patients with androgenic alopecia according to a recent study published in the Journal of Cosmetic Dermatology
A study was conducted to evaluate the efficacy of concentrated growth factor (CGF) injections in patients with androgenic alopecia.
Venous blood of 60 patients (aged 18–55 years old with a mean age of 38 years) with androgenic alopecia who were treated from September 2017 to September 2019 were collected to prepare CGF. 0.1 ml CGF was injected into the alopecia area with an interval of 30–35 days for a total of 6 times. The evaluation was performed before treatment and at 1, 3, and 6 months after the first injection and 3 and 6 months after the last injection.
Results
- Among the 60 patients, 58 cases received 6 treatments completely, 52 cases showed significant improvement, 8 cases improved, and no ineffective or worsening cases were found.
- Among the 58 patients, hair density, hair follicle density, and hair diameter increased significantly. Furthermore, the hair status of all patients was improved to varying degrees during the 6-month follow-up from the digital photographs.
- No complications such as redness, swelling, infection, and ulceration were found in the injection area, and the patient satisfaction was 93% (56/60).
Concentrated growth factor treatment can significantly improve the symptoms of hair loss and increase hair diameter in patients with androgenic alopecia. It is effective, safe, and worth popularizing.
Reference:
Clinical observation and evaluation of CGF in the treatment of androgenic alopecia by Fangning Zhao et al. published in the Journal of Cosmetic Dermatology
https://doi.org/10.1111/jocd.15109
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