Dapsone effective treatment of severe hidradenitis suppurativa

Delhi: Dapsone, in combination with other therapies, may be an effective treatment for patients with moderate to severe with hidradenitis suppurativa (HS), according to recent research. The results were presented at the American Academy of Dermatology's Virtual Meeting Experience (VMX).

Hidradenitis suppurativa is a chronic skin condition characterized by lumps. It affects areas where the skin rubs together, such as the armpits or groin. It develops as a result of inflammation and infection of sweat glands.

HS management is challenging since no single treatment is known to provide consistently effective results and patients often resort to frequent relapses. Few studies have evaluated the efficacy of oral dapsone on HS, especially in the severe form of the disease.

Arjun M. Bashyam, BA, and colleagues conducted the study to determine the efficacy of dapsone on patients with moderate to severe HS.

The researchers conducted a retrospective chart review that involved 19 patients with HS (mean age, 42.7 years; 47.4% white; 68.4% women). They were treated during a 10 year period. The median dose of dapsone was 50 mg with a mean treatment duration of 8.3 months.