Dietary elimination method might improve severe atopic dermatitis symptoms

In individuals with mild to severe atopic dermatitis (AD), dietary elimination may result in a minor, possibly insignificant reduction in the severity of the eczema, pruritus, and insomnia, says an article published in The Journal of Allergy and Clinical Immunology: In Practice.

Skin infections and atopic comorbidities are frequently linked to atopic dermatitis, a chronic inflammatory skin condition characterized by relapsing or persistent pruritus, skin discomfort, lichenification, excoriation, xerosis, and dyspigmentation. Disease activity is thought to be influenced by a variety of factors, such as immune dysregulation, skin barrier dysfunction, and microbial dysbiosis due to internal and external factors. Paul Oykhman and colleagues did this study to comprehensively analyze the advantages and disadvantages of dietary removal for the treatment of AD.

Without regard to language restrictions, we searched MEDLINE, AMED, Embase, PsycINFO, and the Cochrane Central Register of Controlled Trials for randomized controlled trials (RCTs) and observational studies contrasting dietary elimination and no dietary elimination for the treatment of AD from the beginning to January 18, 2022. Also carried out were random-effects meta-analyses of eczema outcomes. To rate the degree of evidence's certainty, the development, assessment, and evaluation approach was used.