Inflammatory skin diseases associated with risk of CKD: Study

The Results of the study are as follows:

The study included 56 602 cases with CKD3–5 and 268 305 controls. Cases were more likely than controls to have a history of atopic eczema [odds ratio (OR) 1·14, 99% confidence interval (CI) 1·11–1·17], psoriasis (OR 1·13, 99% CI 1·08–1·19) or hidradenitis suppurativa (OR 1·49, 99% CI 1·19–1·85), but were slightly less likely to have been diagnosed with rosacea (OR 0·92, 99% CI 0·87–0·97), after adjusting for age, sex, practice (matching factors), index of multiple deprivation, diabetes, smoking, harmful alcohol use and obesity. Results remained similar after adjusting for hypertension and cardiovascular disease. In the cohort with diabetes (N = 335 827), there was no evidence that CKD3–5 incidence was associated with atopic eczema or psoriasis.

Thus, the researchers concluded that atopic eczema, psoriasis and hidradenitis suppurativa are weakly associated with CKD3–5. Future research is needed to elucidate potential mechanisms and the clinical significance of our findings.

Reference:

Inflammatory skin diseases and the risk of chronic kidney disease: population-based case–control and cohort analyses by Y. Schonmann et al. published in the British Journal of Dermatology.

https://doi.org/10.1111/bjd.20067