Is there any association between atopic dermatitis severity and peanut sensitivity? Study sheds light
USA: No significant relationship was observed between measures of atopic dermatitis (AD) severity (POEM and PO-SCORAD surveys) and peanut sensitivity, the authors have stated in a recent study published in JEADV Clinical Practice.
Despite the study's negative results, the researchers add that the "hypothesis that AD can predict peanut sensitivity risk may still be justifiable based on growing evidence. The study results may be due to the use of a small study population due to the limitations of the COVID-19 pandemic. Also, evaluating AD severity through patient-oriented scoring of atopic dermatitis (PO-SCORAD) and Patient-Oriented Eczema Measure (POEM) surveys may be better for pediatric patients.
There is yet to be a widely accepted method for AD severity evaluation among clinicians. Current guidelines from the NIAID (National Institute of Allergy and Infectious Disease) are based on the results of the LEAP Study (Learning Early About Peanut Allergy Study). They recommend the introduction of the early peanut to children with AD, depending on their disease severity.
Against the above background, Sara Bilimoria, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA, and colleagues aimed to determine the association between AD severity (as measured by PO-SCORAD and POEM surveys) and peanut sensitivity as measured by skin prick test or immunoglobulin E (IgE) levels. Secondarily, they also aimed to determine the peanut sensitisation rate in patients with 'mild AD' as defined by a POEM score of 0-7 and a PO-SCORAD score of 1−27.
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