Is there any association between atopic dermatitis severity and peanut sensitivity? Study sheds light

For this purpose, the researchers recruited patients between the age of 3 months and 18 years undergoing IgE or skin prick testing for peanut allergy from two allergy clinics. Patients or their guardians completed a POEM survey and a PO-SCORAD survey.

Between September 2019 and March 2021, 20 patients met the inclusion criteria. The patients' mean age was 19.9 months.

The study led to the following findings:

· Within the 'mild' AD group (PO-SCORAD score 1−27 or POEM score 0−7), the rate of peanut sensitisation was 44% compared to 55% peanut sensitisation amongst all patients participating.

· The type of allergy testing the subjects underwent was left to the treating physician's discretion and was determined before study enrolment.

· Sixteen of the 20 subjects underwent SPT only, two underwent IgE blood testing, and 2 underwent both skin and IgE blood testing.

• There was no significant difference in AD severity measured by PO-SCORAD or POEM score between sexes or age groups (<12 months vs≥12 months).
• No significant relationship was found between POEM or PO-SCORAD scores and the rate of peanut sensitivity.

"We did not find any notable relationship between POEM or PO-SCORAD score and peanut sensitivity; despite this, the hypothesis that AD severity can predict peanut sensitivity may still be justifiable based on a growing body of evidence," the researchers wrote in their study.

Reference:

The study titled "Evaluating the predictive utility of patient-oriented scoring of atopic dermatitis (PO-SCORAD) versus Patient-Oriented Eczema Measure (POEM) for peanut sensitivity in patients with atopic dermatitis" was published in JEADV Clinical Practice.DOI: https://doi.org/10.1002/jvc2.69