Oral Tranexamic Acid Promising in Treatment and Prevention of Post Inflammatory Hyperpigmentation: Study
Researchers have found traditional use of oral tranexamic acid (TXA) as an agent to control excessive bleeding and it is now becoming a safe and effective option to treat post inflammatory hyperpigmentation (PIH). A recent study was published in the journal Dermatologic Surgery by Minasyan and colleagues..
Postinflammatory hyperpigmentation is a common cutaneous disorder due to exaggerated inflammation or injury that results in abnormal pigment deposition in the skin. Although it has long been known as a treatment for melasma, oral TXA is increasingly being considered as an effective treatment of PIH. Indeed, PIH has emerged as one of the most common complications following various skin treatments, including laser-based therapies. Thus, the demand for effective prevention and treatment of PIH is high.
The review was aimed to identify the mechanism of oral TXA in the treatment of PIH and further investigation of its role in preventing PIH associated with laser-based or light-based therapy. The rationale behind this was the collection of data from available studies between 2000 and 2023 that could shed insight into the effectiveness and safety profile of TXA in the context of PIH.
To gather comprehensive data, researchers conducted a systematic review of literature published in the databases such as Cochrane Library, PubMed, Embase, and Google Scholar. The review was conducted using articles that may discuss oral tranexamic acid for the treatment or prevention of PIH and included all studies from 2000 up to now.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.