Oxybutynin effective treatment option for hyperhidrosis

A new study published in Archives of Dermatological Research shows the importance of oxybutynin as a hyperhidrosis therapy must be emphasized for clinicians.

A physiological method of regulating body temperature in humans is sweating. A somatic illness known as hyperhidrosis causes excessive sweating in a specific location due to overactive sweat glands. The sufferers' quality of life is significantly impacted. We want to find out how well oxybutynin works to treat hyperhidrosis and how satisfied patients are with the medication. In order to better understand patient satisfaction and the efficacy of oxybutynin in treating hyperhidrosis, this study was done.

The protocol for this systematic review and meta-analysis was prospectively reported by researchers on PROSPERO. The PRISMA statement reporting requirements were followed while reporting this systematic review and meta-analysis. MeSH phrases were used to search three electronic databases (Scopus, PubMed, and Web of Science) from the beginning through June 2, 2022. Research compared hyperhidrosis patients who got oxybutynin versus a placebo. The Cochrane risk of bias assessment tool (ROB2) for randomized controlled trials was used to evaluate the risk of bias. Using a random effect model with 95% confidence intervals, the risk ratio was estimated for categorical variables, while the mean difference was determined for continuous variables (CI).