Psoriasis Closely Associated to Higher Risk of Kidney Stones Finds Study

Hypernatriuria was found to be significantly higher in the PS group (P = 0.027) by adding another dimension to the metabolic irregularities associated with psoriasis.

Also, the severity of psoriasis appeared to play a role in metabolic abnormalities, with hyperuricosuria detected in 10.4% of patients with severe disease compared to 1.5% in those with mild disease (P = 0.027).

These findings not only underscore a heightened risk of kidney stones in psoriasis patients but also shed light on specific metabolic factors contributing to this increased susceptibility. Hypocitraturia, hyperuricosuria, and hypernatriuria were found as key metabolic abnormalities associated with psoriasis, with hyperuricosuria associated to the severity of the disease.

The findings expand our understanding of the systemic impact of psoriasis and also emphasize the importance of holistic healthcare approaches for individuals suffering with this skin condition. The integration of dermatological considerations along with nephrological issue could prove important in managing and mitigating the risk of urolithiasis in psoriasis patients.

Source:

Oğuz, I. D., Oğuz, U., Usta, M., Kulaklı, S., Tosun, A., Demirelli, E., Akşan, B., Emecen, Ö., & Yüzüak, E. (2023). Relationship between psoriasis and urolithiasis. The Journal of Dermatology. https://doi.org/10.1111/1346-8138.17058