Research Finds Vitiligo Patients May Be More Prone to Metabolic Syndrome
EGYPT: According to a recent study that appeared in the Journal of Cosmetic Dermatology, vitiligo may be regarded as a risk factor for both insulin resistance and the metabolic syndrome.
Research has attempted to examine systemic links with vitiligo in recent decades. Associated systemic autoimmune illnesses have previously been connected to the skin condition.
According to Sarah Ibrahim, MD, of Cairo University's Faculty of Medicine's Department of Dermatology, and colleagues, "the mere presence of vitiligo irrespective of its subtype demands evaluation for accompanying metabolic derangements that tend to develop with advanced age."
Consequently, they continued, "it is crucial to expand the suggested panel of investigations for individuals with vitiligo from the well-documented scope of autoimmune diseases to incorporate metabolic abnormalities."
The researchers aimed to determine if the metabolic syndrome (MetS) and insulin resistance (IR) were linked to vitiligo in various age groups.
The team employed a case-control study design and selected 142 vitiligo patients and 142 controls from the general Egyptian community for the investigation. Patients were evaluated for MetS using the International Diabetes Federation (IDF) criteria and for IR using the homeostasis model assessment of IR (HOMA-IR) when they were under the age of six. Patients who had consumed alcohol in the past, had widespread edema, smoked, or were receiving systemic corticosteroids or other systemic vitiligo therapies were not included in the study. Additionally, they eliminated people who had a history of chronic illnesses, such as neoplastic, collagen, or hematologic conditions.
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