Sclerotherapy for Infantile Hemangiomas improves adverse effects

Sclerotherapy treatments for infantile hemangiomas (IH) and pyogenic granuloma (PG) demonstrated positive outcomes and moderate side effects equivalent to venous malformation (VM), says and article published in Dermatologic Surgery.

The most popular method of treating varicose and spider veins that appear on the legs is sclerotherapy. Additionally, it is utilised to alleviate the hurting, swollen, and burning sensations brought on by these illnesses. A wide variety of disorders known as vascular anomalies cause an aberrant number, configuration, or location of blood vessels.

Many categorization schemes were put out, but it was James Wardrop who distinguished in 1818 between real hemangiomas and the less frequent vascular malformations. The majority of lesions caused by venous malformations can be successfully treated with sclerotherapy. This study was carried out by Chenzi Yang and colleagues to evaluate the efficacy of foam sclerotherapy in treating infantile hemangioma and pyogenic granuloma. They also examined the information and effects of foam sclerotherapy for the venous malformation.

Clinical outcomes, resolution rates, and complication rates were compared for 39 patients with hemangiomas and 83 patients with VMs after treatment. The VM group's sclerotherapy data were also examined.

The key findings of this study were:

The three groups' distribution and tissue involvement of lesions, as well as the patients' average age, were substantially different (p < .001).

While it was less in the PG group than in the infantile hemangioma group (p < .0001), the average volume of sclerosing foam delivered each session in VMs was considerably greater than that in the other 2 groups (p < .0001).

However, there was no discernible difference between the 3 groups in terms of overall treatment effectiveness and side effects.

When treating VMs, the utilization of 3% polidocanol and ultrasound-guided foam sclerotherapy rose from superficial to deep lesions, but the use of 1% POL declined (p < .0001).

Reference:

Yang, C., Li, M., Li, X., Zhu, J., & Shu, C. (2023). Foam Sclerotherapy in the Treatment of Hemangiomas and Venous Malformations. In Dermatologic Surgery. Ovid Technologies (Wolters Kluwer Health). https://doi.org/10.1097/dss.0000000000003857