Some antihypertensive medications increase risk of psoriasis, find studies
Use of antihypertensive mediations and the development of psoriasis, finds analysis of some published studies.The studies indicated that angiotensin-converting-enzyme inhibitors, beta- blockers, calcium-channel blockers, and thiazide diuretics may increase the risk of psoriasis.Therefore, antihypertensive drug users should be carefully monitored for psoriasis.
The analysis is published in the British Journal of Clinical Pharmacology.
Diverse genetic and/or external factors may induce psoriasis. Drug exposure is 1 such prominent external factor; antihypertensive drugs are reportedly associated with psoriasis, but study results have been inconsistent. In this context, we investigated the associations between antihypertensive drugs and incidence if psoriasis via a systematic literature review and meta-analysis.
The researchers carried out literature search in databases such as PubMed, Embase and Web of Science was conducted on 8 January 2021, and obtained data were pooled for meta- and network meta-analysis. Fixed- or random effect models were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for evaluating the strength of the associations between antihypertensive drugs and psoriasis incidence. In addition to meta-analysis, Bayesian network meta-analysis was performed.
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.15060
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