Topical beta-glucan plus nanofractional and magnetic nanofractional radiofrequency effective treatment of stretch marks

Stretch marks are common atrophic dermal scars with significant physical and psychological effects. Therefore, there is a need for effective cosmetics and procedures for stretch mark treatment.Stretch marks affect over half of pregnant women and can lead to a negative self-image, thus impacting their quality of life. Many risk factors that cause stretch marks are difficult to control during pregnancy; therefore, an effective and tolerable treatment modality is required.

Several treatment strategies have been investigated, including the topical application of various creams or oils , superficial dermabrasion [18], trichloroacetic acid peel , platelet-rich plasma , radiofrequency (RF) and laser therapy .

This study aimed to evaluate the efficacy and safety of a novel treatment for stretch marks that is made up of topical formulations containing beta-glucan combined with nanofractional radiofrequency.

This randomized, blinded control trial enrolled 64 Chinese women aged 20–45 years at > 6 months after delivery with obvious white or silver abdominal stretch marks. Participants were randomly allocated to group A (blank group), group B (topical product group), group C (product combined with nanofractional radiofrequency), and group D (vehicle combined with nanofractional radiofrequency). The stretch mark width, skin elasticity, skin color, skin thickness, and collagen density were noninvasively measured. Two trained assessors evaluated the severity, color, outline, and relaxation of the striae.

Results

Group C showed the best treatment efficacy, with no adverse effects observed during the study period.

The findings indicate that stretch mark treatment using topical formulations containing beta-glucan, combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency, is tolerable and effective.

Reference:

Shu, X., Huo, W., Zou, L. et al. Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency. Dermatol Ther (Heidelb) (2023). https://doi.org/10.1007/s13555-023-00926-y