Topical cetirizine effective against androgenetic alopecia, study finds

For this purpose, the researchers searched online databases. Both randomized controlled trials (RCTs) and non-randomized clinical trials were included. Initially, they identified 102 records, of which, two RCTs and one non-randomized clinical trial were included, which were of moderate-to-high risk of bias. 

The researchers wrote, "1% topical cetirizine may serve as a choice for treating AGA, particularly for patients with a negative response to topical minoxidil."

They further add that there is a requirement for additional well-designed RCTs in order to fully understand the role of topical cetirizine for AGA. 

What is androgenetic alopecia?

Androgenetic alopecia is a common type of hair loss seen in both men and women. In men, this condition is also known as male-pattern baldness. Hair is lost in a well-defined pattern, beginning above both temples. 

In women, the pattern of hair loss is different from male-pattern baldness. The hair becomes thinner all over the head, and there is no receding in the hairline. This condition rarely leads to total baldness in women. 

Reference:

Chen X, Xiang H, Yang M. Topical Cetirizine for Treating Androgenetic Alopecia: A Systematic Review. J Cosmet Dermatol. 2022 Aug 17. doi: 10.1111/jocd.15309. Epub ahead of print. PMID: 35976065.