Vitamin D and calcium supplementation reduces nonmelanoma skin cancer risk: Study
USA: Dietary supplementation with calcium alone or in combination with vitamin D reduces the risk of invasive cutaneous squamous cell carcinoma (SCC) but not basal cell carcinoma (BCC), suggests a recent study in the American Journal of Clinical Nutrition.
It is not known whether dietary supplementation with calcium or vitamin D helps in the prevention of keratinocyte carcinomas, also known as nonmelanoma skin cancers. Michael N Passarelli, Geisel School of Medicine at Dartmouth, Hanover, NH, USA, and colleagues aimed to determine whether daily vitamin D or calcium supplementation alters the risk of BCC or invasive SCC.
For the purpose, the researchers conducted the Vitamin D/Calcium Polyp Prevention Study -- a completed multicenter, double-blind, placebo-controlled, partial 2 × 2 factorial, randomized clinical trial of vitamin D, calcium, or both for the prevention of colorectal adenomas. The study included a total of 2259 men and women (45-75 years of age) who were recently diagnosed with colorectal adenoma. They were randomly assigned to 1000 IU/d of vitamin D3 or placebo and 1200 mg/d of calcium carbonate or placebo for 3 or 5 y, and followed after treatment ended. Reports of incident BCC or SCC were confirmed from pathology records.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.