Aortic femoral arterial stiffness gradient independent predictor of mortality among diabetes patients
Aortic-femoral arterial stiffness gradient or afSG may be an independent mortality predictor among diabetic populations, according to a study entitled “Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population-based study.” In J Diabetes on June 16 2023.
Explaining the study background, researchers said that Arterial stiffness leads to additional cardiovascular risks in diabetic patients. It triggers the loss of vascular and myocardial compliance and promotes endothelial dysfunction.
They further said preventing arterial stiffness is a public health priority, and hence biomarkers may be highly significant in early prevention.
Considering these facts and figures, researchers in this study investigated the relationships between serum laboratory tests and pulse wave velocity (PWV) tests. They also study the associations between pulse wave velocity and all-cause mortality.
This study examined a panel of 33 blood biomarkers among diabetic populations in the Atherosclerosis Risk in Communities Study. The carotid-femoral (cfPWV) and femoral-ankle PWV (faPWV) were measured using an automated cardiovascular screening device. They calculated afSG [faPWV divided by cfPWV].
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