Automated insulin delivery improves TIR in hospitalized type 1 diabetes patients without increasing hypoglycemia
Carrera: HCL/AHCL systems with the Automated Mode/SmartGuard feature in patients with type 1 diabetes (T1D) in the hospital environment lead to improved time in range without increasing hypoglycemia, a recent study published in Diabetes Research and Clinical Practice has revealed.
Ana María Gómez Medina and colleagues sought to describe the performance of hybrid closed-loop (HCL) and advanced hybrid closed-loop (AHCL) in the hospital setting based on the continuous glucose monitoring (CGM) metrics description. They revealed that HCL/AHCL systems with active AM/SG in T1D patients in the hospital environment lead to %TIR>70% in ranges of 70–180 mg/dL in patients without an increased hypoglycemia incidence.
The researchers note minimal evidence of the use of hybrid closed-loop/advanced hybrid closed-loop systems for inpatient management. Current guidelines do not include specific recommendations regarding HCL/AHCL systems in the hospital.
The investigators conducted an observational study from a cohort of patients with type 1 diabetes using HCL/AHCL with a history of hospitalization. During the hospital stay, CGM metrics were analyzed. They also performed a CGM metrics sub-analysis of the population with active Automated Mode and SmartGuard during hospitalization and/or surgical procedures. Twenty-four patients were included (50% women; mean age, 49 years).
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