Better glycemic control linked to beneficial effect on bone metabolism, finds study
According to a new study, Glycemic Control and Bone Metabolism Fasting blood glucose levels showed a negative correlation with markers of bone formation and resorption, including total serum procollagen type I N-terminal propeptide (PINP) and age-related type I cross-linked C-telopeptide (CTX). These findings suggest that better glycemic control may have a beneficial effect on bone metabolism.
This study aimed to compare bone metabolism markers between patients with hip fracture who had and did not have type 2 diabetes mellitus (T2DM).MethodsA total of 743 patients with hip fractures were enrolled in this case-control study and were further divided into type 2 diabetes mellitus and non-type 2 diabetes mellitus groups. Biochemical parameters, including fasting blood glucose, triglycerides, and total cholesterol, and bone metabolism parameters, including total serum procollagen type N-terminal propeptide and age-related type I cross-linked C-telopeptide, were collected and compared. Correlations between fasting blood glucose and triglyceride levels and bone metabolism parameters were assessed via Spearman correlation analysis.
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