Bigger waistlines increase risk of fibrosis in diabetes patients with NAFLD: Study
Larger waistlines are linked to progression of non-alcoholic fatty liver disease (NAFLD) in people with type 2 diabetes (T2D), finds study. Each 1cm increase in waist circumference was associated with a 5% higher likelihood of developing advanced fibrosis, a late stage of NAFLD.
The new research has been presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD).
NAFLD, in which fat builds up in the liver can progress to serious liver damage, including advanced fibrosis - potentially life-threatening scarring of the liver.
It is already known that that up to 15-20% of those with T2D have advanced fibrosis. But little is known about what effect, if any, it has on the complications of diabetes.
Dr Tiphaine Vidal-Trécan, of Lariboisiere Hospital, Paris, France, and colleagues studied the relationship in 684 T2D patients.
The participants had an average age of 61, a BMI of 28.7 and a waist circumference of 104cm. 59% were male.
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