Blood selenium levels and diabetic peripheral neuropathy closely related

For this purpose, the researchers selected 51 patients with diabetic peripheral neuropathy and 57 with type 2 diabetes between 2021 and 2022. Blood glucose, Se, and lipid levels were assessed. Electromyographic evoked potentials measured sensory nerve conduction velocity (SNCV) and motor nerve conduction velocity (MNCV) in patients with diabetic peripheral neuropathy.

The study led to the following findings:

• DPN patients exhibited lower Se, SNCV, and MNCV compared to DM patients, with higher glucose and lipid levels.
• Logistic regression analysis identified age, fasting blood glucose, disease duration, and HbA1c as independent risk factors for DPN in type 2 diabetes, while Se emerged as an independent protective factor.

"The findings showed that blood selenium levels and diabetic peripheral neuropathy are closely related, with Se emerging as a significant factor in DPN occurrence among T2DM patients," the researchers concluded.

Reference:

Xu, Hui, et al. "Correlating Blood Selenium Levels in Type 2 Diabetes Mellitus With Peripheral Neuropathy and Factors Contributing to Associated Lesion Development." Alternative Therapies in Health and Medicine, 2023.