CPAP Improves Glycemic Control in Patients with Sleep Apnea and diabetes
CPAP therapy has a notable impact on enhancing HbA1c levels, thereby contributing to improved long-term management of glycemic control in individuals living with type 2 diabetes and obstructive sleep apnea (OSA) finds a study published in European Respiratory Society.
The comprehensive review, which scoured databases including MEDLINE, Embase, Cochrane, and Scopus, examined the effect of CPAP therapy on glycemic control in patients grappling with both OSA and type 2 diabetes. This meta-analysis, involving a random-effect model, assessed outcomes reported in at least two RCTs. Of the 3031 records initially screened, 11 RCTs comprising a total of 964 patients met the criteria for inclusion in the analysis.
The findings of the systematic review provided compelling evidence in favor of CPAP therapy as a means to improve glycemic control in individuals facing the dual challenge of type 2 diabetes and OSA. Notably, CPAP treatment led to a statistically significant reduction in hemoglobin A1c (HbA1c), a key marker of long-term blood sugar control. The mean difference in HbA1c levels between the CPAP-treated group and the inactive control groups was -0.24%, with a 95% confidence interval ranging from -0.43% to -0.06%. This effect was deemed statistically significant with a p-value of 0.001.
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