ECG Abnormalities common in T2D patients even without history of CVD: Study

The American Diabetes Association and the joint European Society of Cardiology and European Association for the Study of Diabetes guidelines recommend a resting ECG in people with type 2 diabetes with hypertension or suspected cardiovascular disease (CVD). However, knowledge of the prevalence of ECG abnormalities is incomplete. Therefore, researchers of the Netherlands conducted a study to analyse the prevalence of ECG abnormalities and their cross-sectional associations with cardiovascular risk factors in people with type 2 diabetes.

The researchers used data collected from 8,068 patients with type 2 diabetes enrolled in the prospective Hoorn Diabetes Care System cohort, which enrolled patients newly diagnosed with type 2 diabetes in the West Friesland region of the Netherlands starting in 1996. They identified ECG abnormalities using the Minnesota Classification and categorised them into types of abnormalities. They calculated the prevalence for the total population (n = 8068) and the subgroup of people without a history of CVD (n = 6494) and used logistic regression models to assess cross-sectional associations.

Key findings of the study were:

• Upon analysis, they found nearly one-third of the total population had minor (16.0%) or major (13.1%) ECG abnormalities.

• Among participants without a CVD history, they found that about one-quarter had minor (14.9%) or major (9.1%) ECG abnormalities.

• Among those with hypertension or very high CVD risk, they noted that the prevalence was 27.5% and 39.6%, respectively.

• They also noted that the ECG abnormalities were significantly and consistently associated with established CVD risk factors.

The authors concluded, "Resting ECG abnormalities are common in all people with type 2 diabetes (29.1%), including those without a history of CVD (24.0%), and their prevalence is related to traditional cardiovascular risk factors such as older age, male sex, hypertension, lower HDL cholesterol, higher BMI, and smoking behaviour."

For further information:

https://doi.org/10.1016/j.jdiacomp.2020.107810