Elevated urine albumin creatinine ratio linked to CV mortality in CAD patients with T2DM
In a recent study entitled, "Elevated urine albumin creatinine ratio increases cardiovascular mortality in coronary artery disease patients with or without type 2 diabetes mellitus: a multicenter retrospective study", Dr Xueqin Lin et al. and colleagues investigated whether mildly elevated Urine albumin creatinine ratio (uACR) can increase the risk of mortality in patients with the history of Coronary artery disease or CAD patients and whether diabetes status influences the risk. In this investigation, they found that with the elevation of uACR level, there is an increased incidence and risk of cardiovascular mortality and all-cause mortality among CAD patients. They highlighted that among type 2 diabetes patients, this risk is more significant.
The elevation increases the risk by nearly 1.5 fold even if the uACR level is within the normal range (recommended by guidelines).
The study is published in Cardiovascular Diabetology.
It is already known that Albuminuria is an atherosclerotic risk factor among the general population. There needs to be more research on the amplification of this association in CAD patients ad whether diabetes mellitus confounds the association.
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