Factory-calibrated CGM accurate for diabetics on hemodialysis: Study
A factory-calibrated continuous glucose monitor (CGM) appears to be reasonably accurate for individuals on hemodialysis, according to a new study.
USA: The study, published in the journal Diabetes Care stated that the factory-calibrated continuous glucose monitor was shown to be resanobaly accurate in its performance and clinically relevant for use in practice by patients on hemodialysis and health professional for improving diabetes management.
CGM display real-time glucose values leading to greater glycemic awareness with reduced management burden. Factory-calibrated CGM systems allow for glycemic assessment sans pain and inconvenience of fngertick glucose testing.
Previous studies have shown that CGM improves diabetes management, but there is no clarity on its reliability in individuals on hemodialysis and is potentially affected by variations in interstitial and intravascular volume. Considering this, Meaghan M. Stumpf, Center for Diabetes Technology, University of Virginia, Charlottesville, VA, and collegaues aimed to assess the accuracy of a factory-calibrated CGM by using venous blood glucose measurements (vBGM) during hemodialysis sessions and self-monitoring blood glucose (SMBG) at home.
Based on the study, the researchers reported the following findings:
- Twenty participants completed the protocol. The mean absolute relative difference of the CGM was 13.8% and 14.4%, when calculated on SMBG (n = 684) and on vBGM (n = 624), and 98.7% and 100% of values in the Parkes error grid A/B zones, respectively.
- Throughout 181 days of CGM monitoring, the median time in range (70–180 mg/dL) was 38.5% (interquartile range 29.3–57.9), with 28.7% (7.8–40.6) of the time >250 mg/dL.
The researchers conclude, "in diabetes patients, the overall performance of a factory-calibrated CGM appears reasonably accurate and clinically relevant for use in practice by individuals on hemodialysis and health professionals to improve diabetes management."
Reference:
Orianne Villard, Marc D. Breton, Swati Rao, Mary K. Voelmle, Morgan R. Fuller, Helen E. Myers, Ryan K. McFadden, Zander S. Luke, Christian A. Wakeman, Mary Clancy-Oliveri, Ananda Basu, Meaghan M. Stumpf; Accuracy of a Factory-Calibrated Continuous Glucose Monitor in Individuals With Diabetes on Hemodialysis. Diabetes Care 7 July 2022; 45 (7): 1666–1669. https://doi.org/10.2337/dc22-0073
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