Fat-to-muscle ratio linked with insulin resistance in adults with type 1 diabetes
China: Fat-to-muscle ratio (FMR) is associated with cardiometabolic disorders (CMD) and insulin resistance (IR) in patients with type 1 diabetes mellitus (T1DM), a recent study has found.
The findings, published in Diabetes, Obesity and Metabolism, could be used as a promising treatment for targeting treatment in type 1 diabetes.
The fat-to-muscle ratio has been proposed as an alternative approach for the assessment of body fat. Xia Li from The Second Xiangya Hospital of Central South University, Changsha, China, and colleagues aimed to investigate the correlation of the fat-to-muscle ratio with insulin resistance and cardiometabolic disorders in patients with type 1 diabetes.
For this purpose, the researchers retrospectively recruited 420 adults with T1DM [52.6% men, median age 32.4 years]. Bioelectrical impedance analysis was used to assess body composition and FMR was calculated. A comparison was drawn of the characteristics of the overall participants between tertiles of FMR. The association of FMR tertiles with IR and cardiometabolic risk factors was assessed using Logistic regression analyses.
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