High levels of serum progesterone associated with Diabetic retinopathy; finds study
Researchers at Qingdao University, Qingdao, China conducted a study to investigate the relationship between serum progesterone (P) and retinopathy in male patients with type 2 diabete (T2DM)and to investigate whether serum progesterone (P) is associated with its progression.
They found that High levels of serum progesterone are significantly associated with Diabetic retinopathy in male hospitalized patients.The findings from a recent trial have been published in Journal of Diabetes Investigation. Researchers further highlighted that higher Progesterone level in men can be a potential clinical factor to identify DR.
The most common complication of type 2 diabetes mellitus (T2DM) is DR, which is a microvascular and neural complication of the retina and remains one of the leading causes of visual loss in adults aged 20–74 years . Interestingly, the male sex has been reported to be an independent risk factor for advanced diabetic retinopathy in T2DM , which suggests the effect of sex hormones. Estrogen can play different roles according to the stage of retinopathy: in the initial stage, the proliferation of endothelial cells induced by estradiol has a beneficial effect and protects the retina through the induced repair process, while in the proliferative phase, this effect aggravates the retinopathy .
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