Hybrid closed-loop insulin therapy effectively improves blood sugar control in T1D

"Notably, we found that this sample of adolescents and young adults successfully used the CGM more than 90% of the time during the 6-month trial and the closed-loop system was active 89% of the time," stated John Lum, Jaeb Center for Health Research, and the iDCL Trial Research Group.

The researchers concluded that use of closed-loop control for 6 months was substantial and associated with improved TIR and reduced hypoglycemia in adolescents and young adults with type 1 diabetes. Thus, closed-loop control has the potential to improve blood sugar outcomes in this challenging age group.

"Multiple Automated Insulin Delivery (AID) systems using different algorithms have been developed in the past decade for patients with type 1 diabetes. Almost all of the systems have shown significant reductions in nocturnal hypoglycemia. The iDCL multicenter trial done in young adults and adolescents with T1D reported in this issue of DTT further advances the use of hybrid closed-loop system by increasing the time-in-range, especially during the night," says Satish Garg, MD, University of Colorado Denver and Editor-in-Chief of Diabetes Technology & Therapeutics.