Increased Risk of Diabetes Observed in Childhood Cancer Survivors: Study
A recent study published in the recent issue of Diabetes Care journal revealed a significant long-term risk of diabetes among survivors of childhood and young adult cancer (CYAC). This researchers has identified key cancer treatments like total body irradiation (TBI), hematopoietic stem cell transplants (HSCT), and corticosteroids, as major contributors to the development of diabetes over time.
The study analyzed data from over 4,200 cancer survivors through linked cancer registries and electronic health records which found the extent of diabetes risk and treatment-specific influences on its onset. This research utilized clinical coding and HbA1c values to identify diabetes cases and assess cumulative incidence rates over a 40-year period.
After a median follow-up period of 14.4 years, almost 163 individuals (3.8%) in the cohort were diagnosed with diabetes. The risk varied significantly depending on the type of cancer treatment received. The survivors treated with total body irradiation (TBI) demonstrated a stark increase in long-term diabetes risk. By the 40-year mark, 21% of patients exposed to TBI had developed diabetes when compared to just 8.4% of the patients who did not undergo the treatment.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.