Intermittent very low-calorie diet tied to diabetes remission in adults with obesity: Study

The results of the study are as follows:

• A total of 40 participants were enrolled.
• The mean body mass index was 30.1 ± 5.9 kg/m2, and the mean glycated haemoglobin was 7.4 ± 1.2%. At week 20, there was an improvement in glycemic control in both intermittent VLCD groups with significant decreases in glycated haemoglobin levels and insulin resistance index throughout the study periods.
• Diabetes remission without the need for medications was equally found in 29% of participants in both intermittent VLCD groups.
• Serum triglyceride, bodyweight, body mass index and fat mass were also significantly decreased in both VLCD groups.
• No serious adverse events were encountered.

Thus, the researchers concluded that intermittent very-low-calorie diet (VLCD) was highly effective in achieving optimal glycemic control. The effects of 2 days/week and 4 days/week of intermittent very-low-calorie diet (VLCD) on diabetes remission were relatively similar.

Reference:

Effects of an intermittent very-low-calorie diet on glycemic control and cardiovascular risk factors in obese patients with type 2 diabetes mellitus: A randomized controlled trial by Umphonsathien M et. al published in the Journal of Diabetes Investigation.

https://doi.org/10.1111/jdi.13619