Lower parasympathetic activation and Depression linked to poor Glycemic control in diabetics

In patients with Type 2 Diabetes, lower parasympathetic activation and higher depressive symptoms affected the Glycemic control as per a recent study that was published in "Journal of Diabetes and its complications, 2022."  

Dysfunctions of the autonomic nervous system (ANS) and comorbidities associated with depression or anxiety are some of the symptoms exhibited by patients with T2 diabetes having poor glycemic control. By using the Heart rate variability (HRV) converted from ECG as the ANS index, researchers from Taiwan conducted a study to explore the association between depression, anxiety, HRV, and glycemic control in patients with type 2 diabetes mellitus. 

647 patients with type 2 diabetes mellitus participated in the study. The Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) questionnaires were given to the patients to assess depression and anxiety symptoms. ECG raw signals were transformed to HRV indices referring ANS activation after collecting them from a 5-min sitting and resting baseline. From the electronic media records other parameters like Blood glucose and lipid profiles including glycated hemoglobin (HbA1c), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglyceride were obtained.