Omega-3 supplementation boosts glucose and lipid metabolism in women with gestational diabetes
China: Omega-3 supplementation in patients with gestational diabetes mellitus (GDM) can reduce inflammatory factors and fasting plasma glucose (FPG) levels, reduce insulin resistance, and enhance blood lipid metabolism, a meta-analysis of randomized controlled trials has shown.
The research was published online in the April 2023 issue of the Journal of Diabetes and its Complications.
Gestational diabetes is an impairment of glucose tolerance and insulin resistance that begins during pregnancy. Its estimated prevalence is 14.0 %, making it one of the most pregnancy complications harmful to the fetus and the mother. Insulin resistance is closely linked with glucose metabolism disorder in gestational diabetes. Pregnant women affected by GDM are at a much higher risk of type 2 diabetes and pre-eclampsia development, and eventually, 70% of these women develop diabetes after 22–28 years of delivery.
Omega-3 (omega-3 fatty acid) is a polyunsaturated fatty acid mainly containing docosahexaenoic acid, eicosapentaenoic acid from marine organisms, and α-linolenic acid. Omega-3 has received a lot of attention due to its several biological actions. One randomized controlled trial showed that omega-3 supplementation of 1000 mg/day improved insulin resistance in GDM patients without affecting lipid and glucose metabolism. Another study showed that omega-3 supplementation could improve lipid and blood glucose levels in GDM.
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