Postural Variation In DLCO Identifies Pulmonary Microangiopathy in T2DM patients
Diabetes-related microvascular and macrovascular complications cause a significant increase in morbidity and mortality.
A recent study suggests that postural variation in Diffusion capacity for carbon monoxide (DLCO) is a useful test in identifying pulmonary microangiopathy among patients with Type II diabetes mellitus (T2DM). The study findings were published in the Diabetes & Metabolic Syndrome: Clinical Research & Reviews on December 15, 2021.
Lower Forced Vital capacity (FVC), Forced Expiratory Volume in the first second (FEV1) & DLCO occurs in adults with T2DM compared to non-diabetic individuals. Reduction in lung function correlates with glycemic status and duration of diabetes independent of smoking or obesity. Still, the entity of pulmonary microangiopathy is often under-recognized clinically and its awareness among general practitioners managing diabetes remains low likely due to its subclinical lung function abnormalities. Therefore, Dr Arun K and his team conducted a study assessing the occurrence of pulmonary microangiopathy among T2DM using dynamic DLCO.
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