Tubeless insulin pump therapy tied to good glycemic control and low frequency of DKA in Diabetes
Tubeless insulin pump therapy is significantly associated with decreased rates of severe hypocalcemia (SH) and diabetic ketoacidosis (DKA) primarily in pediatric and adolescent population that is prone to these complications, finds a new study.
Despite the typical age-dependent increase in HbA1c through adolescence, glycemic control with tubeless insulin pump use compares favorably with other large registry data.In addition, high treatment retention rates were observed in patients with type 1 diabetes of all ages initiating tubeless insulin pump use.
The study has been published in Diabetes Technology & Therapeutics.
A study was conducted by a group of researchers from Germany and Austria to characterize patients with diabetes treated with a tubeless insulin pump (Omnipod® Insulin Management System; Insulet Corp., Acton, MA), and to evaluate the frequency of acute complications with long-term use of the system.
The researchers conducted the retrospective analysis of the German/Austrian Diabetes Patienten Verlaufsdokumentation (DPV) registry that included data from 3657 patients with diabetes treated with a tubeless insulin pump. Hemoglobin A1c (HbA1c) levels and frequency of diabetic ketoacidosis (DKA) and severe hypoglycemia (SH) were compared between 1-year pre- and 1 year (n = 2911) or up to 3 years (n = 1311) post-tubeless insulin pump initiation and compared with a contemporary cohort on multiple daily injections (MDI) with 3-year data (n = 1874).
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