Vitamin D deficiency tied to dyslipidemia in type 2 diabetes complicated with obesity and CAD: Study
Saudi Arabia: In type 2 diabetes, the deficiency status of vitamin D was shown to be associated with dyslipidemia, particularly those complicated with coronary artery diseases and obesity, a recent study in Clinical Laboratory has revealed.
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease leading to vascular complications. Amal F. Gharib, Taif University, Ta'if, Saudi Arabia, and colleagues aimed to investigate the relationship between vitamin D deficiency, dyslipidemia, and obesity with the risk of coronary artery disease in type 2 diabetes.
The study included 200 Saudi adult participants, aged 40 - 60 years, of both genders, who attended King Abdulaziz Specialist Hospital in Taif city. The subjects were categorized into four groups; the control group, type 2 diabetes, type 2 diabetes with coronary artery disease (CAD), and type 2 diabetes with obesity having body mass index (BMI) ≥ 30 kg/m2; 50 subjects were included in each group.
The researchers estimated fasting blood glucose (FBG), serum vitamin D (25-OH-D), high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), glycosylated hemoglobin (HbA1c), and triglycerides (TG) levels.
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