Association between vitamin D and type 2 diabetes is affected by magnesium intake, study finds

For this purpose, the researchers analyzed data from the National Health and Nutrition Examination Survey (NHANES) continuously from 2007 to 2014, including 10,249 participants. The subjects were stratified based on magnesium intake category (low magnesium intake <267 mg/day; high magnesium intake: ≥267 mg/day). Further, the researchers evaluated the difference (interaction test) between the relationship of vitamin D with the risk of T2D among low magnesium intake participants and high magnesium intake participants. 

Based on the study, the team found that the the association of serum vitamin D with the incidence of T2D appeared to differ between the low magnesium intake group and the high magnesium intake group (OR: 0.968). Furthermore, they found a evidence of interaction between vitamin D levels and magnesium intake on decreasing the incidence of T2D. 

These results indicate that that magnesium intake might affect the association of serum vitamin D with the risk of T2D," wrote the authors. "Such a finding requires further randomized controlled trials to provide more evidence."

Reference:

The study titled, "Dietary Magnesium Intake Affects the Association Between Serum Vitamin D and Type 2 Diabetes: A Cross-Sectional Study," was published in the journal Frontiers in Nutrition on 25 November 2021. 

DOI: https://doi.org/10.3389/fnut.2021.763076