Factors Beyond Carbs Might Influence Post Prandial Blood Glucose in T1DM Patients
Carbohydrates (CHOs) are the main determinants of postprandial glucose response (PGR). However, a study suggests that nutritional factors other than the amount of carbohydrates significantly influence postprandial blood glucose control. The study findings were published in the Diabetologia on October 23, 2021.
A hybrid closed-loop system (HCLS) automatically delivers basal insulin according to an algorithm based on continuous glucose monitoring (CGM). However, there is very little information on the nutritional factors influencing postprandial glucose control in individuals with type 1 diabetes on HCLSs. Therefore, Dr Giovanni Annuzzi and his team conducted the first study to evaluate the relationship between meal nutrients and PGR in individuals with type 1 diabetes on an HCLS.
The researchers assessed the dietary composition of 1264 meals (398 breakfasts, 441 lunches and 425 dinners) was assessed by 7-day food records completed by 25 individuals with type 1 diabetes on HCLSs. For each meal, they evaluated the PGR (continuous glucose monitoring metrics, glucose incremental AUCs) and insulin doses (pre-meal boluses, post-meal micro boluses automatically delivered by the pump and adjustment boluses) over 6 hours.
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