Higher fibre intake may improve High Bowel Symptom Burden in CRC Survivors: JAMA

Written By :  Dr. Shravani Dali
Published On 2025-12-01 15:30 GMT   |   Update On 2025-12-01 15:30 GMT
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A recent cohort study published in JAMA Network Open by Klaassen-Dekker and colleagues has shown that bowel-related symptoms persist for years after a colorectal cancer diagnosis and treatment. The research followed a large group of survivors for up to five years and found that nearly half reported symptoms such as diarrhea, urgency, or mucus in stools six months post-diagnosis, with more than one-third still affected five years later. Importantly, the study revealed that higher dietary fibre intake was associated with a lower prevalence of diarrhea, suggesting that diet may play a key role in improving quality of life for colorectal cancer survivors.

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The study analysed survivors recruited at diagnosis and followed them at 6 months, 2 years and 5 years after surgery. Patients who reported higher fibre intake—estimated from validated questionnaires—showed significantly reduced rates of moderate to severe diarrhea at the 6-month and 2-year time points. The researchers emphasised that this was independent of major treatment differences, such as chemotherapy or radiotherapy, and that dietary modification may offer a non-pharmacological strategy to manage long-term bowel dysfunction after cancer therapy.

Clinically, these findings suggest that dietary counselling and nutritional support should become standard components of survivorship care in colorectal cancer. Given the high burden of persistent bowel symptoms and their impact on quality of life, healthcare teams should emphasise fibre-rich diets as part of long-term follow-up. While further research is needed to define optimal fibre amounts and to explore effects on other gut symptoms, the evidence supports integrating nutrition into post-cancer care for better patient outcomes.

Keywords:

colorectal cancer survivors, bowel symptoms, dietary fibre intake, diarrhea, cancer survivorship, nutritional counselling

Reference:
Klaassen-Dekker, N., Witteman, B. J. M., van de Poll-Franse, L. V., Beekman, J., Heine-Bröring, R., May, A. M., ... & van Buurden, M. (2025). Bowel-related symptoms and dietary fiber intake in colorectal cancer survivors: A cohort study. JAMA Network Open, 8(11), e2841184. https://doi.org/10.1001/jamanetworkopen.2025.2841184


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Article Source : JAMA

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