Intake of fish oil supplements tied with lower risk of all-cause dementia: Study
Intake of fish oil supplements is associated with lower risk of all-cause dementia, according to a recent study published in the Clinical Nutrition.
Evidence linking the use of omega-3 PUFA supplements with incident dementia is scarce. Researchers aimed to assess the relationship between fish oil supplementation and incident dementia risk among older adults with different apolipoprotein E (APOE) genotypes in a large population-based cohort.
The researchers included 215,083 participants (average age: 64.1 ± 2.9 y) without dementia at baseline from UK Biobank study. Fish oil use was assessed by a touch screen questionnaire at baseline. Dietary intake was assessed by a food frequency questionnaire. The APOE genotypes were determined by allele variations on rs429358 and rs7412 from genome-wide genotyping of blood samples. Dementia was diagnosed using the International Classification of Diseases (ICD-9 and ICD-10). Cox proportional hazards regression models were used to calculating the associations of fish oil supplement use with dementia risk.
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