Is Ketogenic diet effective in patients with breast cancer?

Written By :  Jacinthlyn Sylvia
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2023-11-09 11:30 GMT   |   Update On 2023-11-09 11:31 GMT
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Breast cancer, a complex disease influenced by numerous factors, is increasingly linked to dietary habits. The ketogenic diet (KD), characterized by high fat and low carbohydrate intake, has piqued interest as a potential therapeutic approach. A recent review published in Nutrients Journal shed light on the potential role of KD in breast cancer management.

This comprehensive literature review focused on both preclinical and clinical studies, with a key emphasis on how the KD affects breast cancer cells metabolically and its role in current clinical trials. The studies yielded a range of findings: some suggest the KD may inhibit tumor growth and enhance treatment response. 

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The findings from these studies suggest that the KD could inhibit tumor growth and enhance treatment response. However, there's a significant gap in well-structured clinical trials providing conclusive evidence of the KD's efficacy as a standalone treatment for breast cancer. Safety concerns also persist, particularly regarding the long-term effects of sustained ketosis in cancer patients.

The therapeutic potential of the KD in breast cancer remains a subject of active research and debate. While initial results are promising, inconsistent outcomes and limited human trial data hinder definitive conclusions.

Therefore, the call is for future research, especially large-scale, rigorously designed clinical trials, to offer a more comprehensive understanding of the KD's role in breast cancer treatment. Until this happens, caution should prevail in its application, and patients are advised to continue prioritizing evidence-based, standard-of-care treatments.

The link between diet and breast cancer is a critical area of study, and the KD could hold promise. However, with much still unknown, prudence in decision-making remains essential in the realm of breast cancer treatment.

Source:

Urzì, A. G., Tropea, E., Gattuso, G., Spoto, G., Marsala, G., Calina, D., Libra, M., & Falzone, L. (2023). Ketogenic Diet and Breast Cancer: Recent Findings and Therapeutic Approaches. In Nutrients (Vol. 15, Issue 20, p. 4357). MDPI AG. https://doi.org/10.3390/nu15204357

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Article Source : Nutrients

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