Short-Term Vegan Diet Linked to Epigenetic Age Benefits and Lower Calorie Intake, Study Finds
USA: An article published in BMC Medicine revealed that a brief vegan diet can lead to epigenetic age improvements and a decrease in calorie consumption.
The application of epigenetic biomarker proxies (EBPs) underscores their promise in evaluating dietary effects and enabling personalized nutrition approaches for promoting healthy aging, the researchers wrote.
Geroscience aims to develop interventions that counteract the molecular changes linked to aging. While lifestyle changes, medications, and social factors can influence the aging process, the intricate molecular mechanisms involved necessitate a thorough examination of the epigenetic landscape. The precise effects of a vegan diet on the epigenetic clock and aging predictors, compared to an omnivorous diet, have not been extensively studied, despite their potential impact on aging outcomes.
Varun B. Dwaraka, TruDiagnostic, Inc, 881 Corporate Dr, Lexington et. al. conducted a study to determine the effects of an 8-week plant-based or healthy omnivorous diet on blood DNA methylation in twins. They also aimed to evaluate age-related risk factors and health biomarkers. The uniqueness of this study lies in its twin-pair design, which controls for genetic, age, and sex differences while focusing on diet-induced methylation changes. Notably, this is the first study to examine the impact of epigenetic measures using a twin-pair study design, specifically investigating whether diet influences these measures.
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