Sugary drinks and processed foods may damage immune system, finds study
UK: The consumption of diet high in sugar fructose may prevent the proper functioning of one's immune system, a recent study has revealed. The study is published in the journal Nature Communications.
High fructose foods include sugary drinks, processed foods and sweets and also, fructose is used widely in food production. It is associated with the development of type 2 diabetes, obesity, and non-alcoholic fatty liver disease. In recent years, its intake has increased substantially throughout the developed world. However, information on the impact of high level consumption of fructose on the immune system, has been limited until now.
Against this background, Catherine A. Thornton, Swansea University, Swansea, UK, and colleagues show that fructose reprograms cellular metabolic pathways to favour glutaminolysis and oxidative metabolism, which are required to support increased inflammatory cytokine production in both LPS-treated human monocytes and mouse macrophages. Monocytes and macrophages are immune cells.
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